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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STK4 All Species: 23.64
Human Site: S345 Identified Species: 40
UniProt: Q13043 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13043 NP_006273.1 487 55630 S345 M G T V R V A S T M T D G A N
Chimpanzee Pan troglodytes XP_001153224 503 57116 S361 M G T V R V A S T M T D G A N
Rhesus Macaque Macaca mulatta A4K2T0 487 55587 S345 M G T V R V A S T M T D G A S
Dog Lupus familis XP_534432 487 55507 S345 M G T V R V A S T T S D G A S
Cat Felis silvestris
Mouse Mus musculus Q9JI11 487 55523 S345 M G T V R V A S T M S G G A N
Rat Rattus norvegicus O54748 491 56103 S341 V G T M R A T S T M S E G A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518508 281 31761 Y162 E V I Q E I G Y N C V A D I W
Chicken Gallus gallus Q5ZJK4 486 55318 N344 T G T I R V V N T M S D G A N
Frog Xenopus laevis Q6PA14 485 55246 G345 L N T M K E L G M M S E G A D
Zebra Danio Brachydanio rerio Q7ZUQ3 492 56062 G341 A G T M R A T G T M S D G A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T0S6 669 75091 S407 A A P A A A S S A A S P L D M
Honey Bee Apis mellifera XP_393691 465 52970 G336 K P L P E D T G T L V P S H D
Nematode Worm Caenorhab. elegans Q9NB31 497 55620 S358 S L R S Q M E S L R I G G E I
Sea Urchin Strong. purpuratus XP_781787 488 55060 N346 I I S G S A G N T A N T F I E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.6 99.3 97.3 N.A. 97.3 78 N.A. 55.8 92.1 76.5 77 N.A. 45.4 62.4 52.3 64.9
Protein Similarity: 100 95.8 99.7 98.9 N.A. 98.5 89.6 N.A. 57.2 96.5 86.8 87.4 N.A. 58.5 77.8 68.4 79.1
P-Site Identity: 100 100 93.3 80 N.A. 86.6 53.3 N.A. 0 66.6 26.6 53.3 N.A. 6.6 6.6 13.3 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 80 N.A. 6.6 86.6 66.6 66.6 N.A. 20 20 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 8 8 29 36 0 8 15 0 8 0 65 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 43 8 8 15 % D
% Glu: 8 0 0 0 15 8 8 0 0 0 0 15 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 58 0 8 0 0 15 22 0 0 0 15 72 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 8 8 8 0 8 0 0 0 0 8 0 0 15 8 % I
% Lys: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 8 8 0 0 0 8 0 8 8 0 0 8 0 0 % L
% Met: 36 0 0 22 0 8 0 0 8 58 0 0 0 0 8 % M
% Asn: 0 8 0 0 0 0 0 15 8 0 8 0 0 0 29 % N
% Pro: 0 8 8 8 0 0 0 0 0 0 0 15 0 0 0 % P
% Gln: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 15 % Q
% Arg: 0 0 8 0 58 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 8 0 8 8 8 0 8 58 0 0 50 0 8 0 15 % S
% Thr: 8 0 65 0 0 0 22 0 72 8 22 8 0 0 0 % T
% Val: 8 8 0 36 0 43 8 0 0 0 15 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _